C18 - Stainless Steel Columns
C18 is often called the "traditional reverse phase matrix” because it has the highest degree of hydrophobicity. C18 silica gel interacts with the widest range of compounds and the interactions are generally more pronounced. The reason why C-18 is more hydrophobic than the other reverse phases is because the length of the carbon chains are longer (i.e. C18 is longer than C8, and C8 is longer than C4 etc).
C18 - Stainless Steel Columns
C18 is often called the "traditional reverse phase matrix” because it has the highest degree of hydrophobicity. C18 silica gel interacts with the widest range of compounds and the interactions are generally more pronounced. The reason why C-18 is more hydrophobic than the other reverse phases is because the length of the carbon chains are longer (i.e. C18 is longer than C8, and C8 is longer than C4 etc).